CJC-1295 with DAC vs. Modified GRF (1-29): the drug affinity complex extends hal

CJC-1295 with DAC vs. Modified GRF (1-29): the drug affinity complex extends hal

“CJC-1295” is used for two backbones. One carries a C-terminal Lys with a maleimidopropionyl (DAC) handle. The other is tetrasubstituted GRF(1–29) amide without that handle (often sold as “CJC-1295 no DAC” or modified GRF 1-29). They are different formulae and different masses. This site does not list either as a catalog SKU.

RUO. Laboratory reagent listing. Not for human or veterinary use. Not a medicine, food, cosmetic, or supplement. Lot HPLC, MS, and net peptide content, when issued, live on the lot COA — we do not invent a percentage on this page.

How to tell them apart

With DACNo DAC (mod GRF 1-29)
Formula (typical)C165H269N47O46C152H252N44O42
Nominal MW~3647 Da~3368 Da
PubChemCID 91971820related records around CID 56841945 / 91976842
CAS in circulationoften 446262-90-4863288-34-0 is deprecated and often mis-paired

A user-facing spec that prints CAS 863288-34-0 with DAC is the pairing FDA’s compounding committee flagged as unreliable.2 Believe formula and observed mass of the maleimide, not the nickname. We will not invent HPLC% for a molecule we do not list.

The GHRH-class listing actually on this catalog is Tesamorelin / Ipamorelin — a different analogue, with its own two CAS numbers.

The difference between the impossible and the possible lies in a person's determination. — Tommy Lasorda

What we actually list

Tesamorelin and ipamorelin as named components. Not CJC-1295.

View that blend →

References

  1. PubChem CID 91971820, Cjc 1295. Formula C165H269N47O46. https://pubchem.ncbi.nlm.nih.gov/compound/91971820
  2. FDA Pharmacy Compounding Advisory Committee, 4 Dec 2024, briefing on CJC-1295-related bulk substances (CAS pairing errors). https://www.fda.gov/media/183891/download