By BioLabs Research · Last reviewed: October 28, 2026
BPC-157 is a synthetic peptide made of 15 amino acids, a pentadecapeptide. Its sequence is a fragment of a larger protein, named BPC, that was first isolated from gastric juice [2]. BioLabs Research supplies BPC-157 as a lyophilized research material for laboratory and in-vitro work only.
Popular write-ups about BPC-157 tend to skip the paperwork. This page does the opposite: it sets out what the molecule is, what the published laboratory literature has measured, and what a lot certificate should show so a receiving lab can confirm which material it holds. It is an identity and documentation reference, not a protocol of any kind.
BPC-157 peptide: molecular identity
| Property | Value |
|---|---|
| Sequence | Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val (GEPPPGKPADDAGLV) |
| Full notation | H-Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val-OH |
| Length | 15 amino acids |
| Molecular formula | C62H98N16O22 |
| Molecular weight | 1419.5 g/mol (average) |
| Monoisotopic mass | 1418.70 Da |
| CAS number | 137525-51-0 |
| PubChem CID | 9941957 |
| Form supplied | Lyophilized powder, 10 mg and 20 mg vials |
Values are from the PubChem record [1]. Check them against the COA for the lot you hold rather than against catalog values.
Where the name comes from
"BPC" stands for body protection compound, the name the original research group gave to the larger protein they isolated from gastric juice in the early 1990s [2]. BPC-157 is a 15-residue stretch of that protein, made synthetically. The number is part of the catalog name and does not describe a property of the molecule. Because the sequence is short and fully defined, its identity can be confirmed analytically: the sequence, formula and mass in the table above are the fields a certificate should match.
What published research on BPC-157 has looked at
Most BPC-157 literature comes from animal and cell-culture models. A few examples of what has been measured:
- Nitric-oxide (NO) system. A review by the group that first described the peptide covers its relationship with NO signaling in experimental models [3].
- Receptor expression in cultured cells. A cell-culture study measured growth hormone receptor expression in rat tendon fibroblasts exposed to BPC-157 [4].
- Endothelial signaling. A study on isolated rat aorta examined nitric oxide generation and the Src–caveolin-1–eNOS pathway [5].
These are observations from laboratory models. They are not evidence of safety or efficacy in people, and BioLabs Research makes no such claims. We list the studies so readers can go to the primary record; the summaries above describe what was measured, not what any result would mean outside the model in which it was observed.
Stability in the literature
The group that first described BPC-157 calls it a "stable gastric pentadecapeptide" and reports it as stable in human gastric juice [3]. How a given lot behaves in an experiment depends on storage and handling, and is for the lab to confirm.
BPC-157 vs TB-500: different molecules
BPC-157 is often listed next to TB-500, and the two are sometimes sold together as a blend. They are unrelated sequences. BPC-157 is a 15-residue fragment of a gastric-juice protein, about 1419.5 g/mol. TB-500 is a 7-residue, N-acetylated fragment of thymosin beta-4, about 889 g/mol. Different sequences give different masses, so a mass spectrometry result separates them immediately. A blend certificate should report each component separately, with its own observed mass. For the identity of each, see What is TB-500? and BPC-157 / TB-500 blend: two sequences, two masses; for the catalog comparison, see BPC-157 vs TB-500.
How to verify a BPC-157 lot
A lot's certificate of analysis (COA) should let you check four things:
- HPLC chromatogram. Purity as area percent of the total peak area at a stated wavelength. Area percent is not net peptide content; see HPLC area percent vs net peptide content.
- Mass spectrometry (MS). The observed mass should match the expected value: 1418.70 Da monoisotopic, 1419.5 g/mol average [1].
- Lot number and test date. These tie the document to the exact vial you hold.
- Testing laboratory. The certificate should name the lab that ran the analysis and the method used. If a certificate cites an accreditation such as ISO/IEC 17025, it can be checked in the accreditation body's public directory.
Lab COA PDFs are published in our COA library. For a field-by-field walkthrough, see how to read a peptide COA; for a wider checklist, see how to verify a peptide supplier.
Receiving checklist for a BPC-157 lot
Before a vial is booked into inventory, confirm:
- The carton, the order and the invoice all name the same catalog listing and vial size.
- The lot number on the vial appears on the certificate.
- The certificate prints the 15-residue sequence and an expected mass consistent with 1418.70 Da (monoisotopic) or 1419.5 g/mol (average).
- The observed mass reported by the testing lab agrees with that expected value.
- The HPLC method (column, wavelength) is identified next to the area-percent figure.
- The vial is sealed, dry and intact.
If any field disagrees, record the lot as "identity unresolved" and ask for a corrected certificate. Keep each record tied to a distinct receiving check (label identity, lot paper, pack condition) so an audit can be reconstructed later.
What to look for in a supplier's documentation
When comparing sources of BPC-157 for laboratory use, the useful questions are documentary:
- Lot traceability. Every lot has a unique identifier that appears on both the vial and the certificate.
- Named testing laboratory. The certificate identifies who ran the analysis.
- Lot-specific purity. Purity is reported per lot on the COA, not as a single catalog-wide number.
- Clear, published pricing. Research materials should have transparent pricing and written quotes for multi-vial orders.
Storage and safety data
BPC-157 ships as a sealed, lyophilized solid. Its safety data sheet lists storage at 2–8 °C or below, in the original sealed vial, protected from light and moisture. Download it from the SDS library. Log the receipt date, storage location and lot number against the certificate, and follow institutional chemical-hygiene and disposal rules.
Frequently asked questions
Is BPC-157 approved for human use?
No. Drugs@FDA lists no approved drug product containing BPC-157. BioLabs Research sells it for laboratory research only, not for human or veterinary use.
What does BPC stand for?
Body protection compound. BPC-157 is a 15-amino-acid fragment of a larger protein named BPC that was isolated from gastric juice.
What is the molecular weight of BPC-157?
1419.5 g/mol average, with a monoisotopic mass of 1418.70 Da and formula C62H98N16O22 (PubChem CID 9941957). Confirm it against the MS result on your lot's COA.
What is the difference between BPC-157 10 mg and 20 mg?
Only the amount of material in the vial. The peptide and its identity are the same, and each lot has its own COA.
Where do I find the purity of a BPC-157 lot?
On the COA for that lot, as an HPLC area-percent figure at a stated wavelength. We do not publish a purity number without a lot behind it. Request the COA from the product page or the contact form with the lot number.
Is BPC-157 the same as TB-500?
No. BPC-157 is a 15-amino-acid fragment of a gastric juice protein. TB-500 is a 7-residue acetylated fragment of thymosin beta-4. They have different sequences and different masses.
View BPC-157 research material →
References
- National Center for Biotechnology Information. PubChem Compound Summary for CID 9941957, BPC-157. https://pubchem.ncbi.nlm.nih.gov/compound/9941957
- Sikirić P, Petek M, Rucman R, et al. A new gastric juice peptide, BPC. […] J Physiol Paris. 1993;87(5):313–327. doi:10.1016/0928-4257(93)90038-u. PubMed 8298609
- Sikiric P, Seiwerth S, Rucman R, et al. Stable gastric pentadecapeptide BPC 157-NO-system relation. Curr Pharm Des. 2014;20(7):1126–1135. doi:10.2174/13816128113190990411. PubMed 23755725
- Chang CH, Tsai WC, Hsu YH, Pang JH. Pentadecapeptide BPC 157 […] growth hormone receptor expression in tendon fibroblasts. Molecules. 2014;19(11):19066–19077. doi:10.3390/molecules191119066. PubMed 25415472
- Hsieh MJ, Lee CH, Chueh HY, et al. […] BPC 157 on vasomotor tone and the […] Src-Caveolin-1-endothelial nitric oxide synthase pathway. Sci Rep. 2020;10(1):17078. doi:10.1038/s41598-020-74022-y. PubMed 33051481